Saturday, October 17, 2015

Epidemiology of HIV- Wasting Syndrome



 

                A study- Nutrition for Healthy Living (NFHL) that has been done in Boston, US from 1995-2005 looked at 881 patients with HIV around age 40; 29% were women and 44% were non-white race. In this study some of the symptoms and causes of HI-wasting syndrome were identified. Causes that fell into two possible groups: 1) inadequate nutrient intake, and 2) altered nutrient metabolism were socioeconomic status, access to care, cultural practices, psychological factors, and medical complications of therapies.

Symptoms included inadequate nutrient intake, oral and gastrointestinal symptoms, anorexia, psychosocial-economic symptoms, malabsorption, uncontrolled HIV infection, and metabolic demands of HAART (highly active antiretroviral therapy).

33.5% of the 881 HIV infected patients met the criteria of either having 1) loss of more than 10% of body weight, 2) loss of more than 5% of body weight that was sustained for longer than 6 months and lastly 3) had a BMI (body mass index) of less than 20 (normal BMI range: 18.5-25.0).

The study showed that more men than women had diarrhea, and women showed greater deficiencies in vitamins A, C, E, and B₆.  38.4% women had insufficient caloric intake. 11.3% had inadequate protein intake, 36.1% weren’t sure where they were going to get their next meal from, and 8% identified themselves as hungry.

 

 

 

 

 

 

 

Reference

 

Mangili, A. M. Zampini, D. H. Murman, & C. A. Wanke (February 7, 2006). Nutrition and HIV Infection: Review of Weight Loss and Wasting in the Era of Highly Active Antiretroviral Therapy from the Nutrition for Healthy Living Cohort. Invited Article, CID 2006; 42, 836-842. Retrieved from http://cid.oxfordjournals.org/content/42/6/836.full.pdf+html

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